Membrane potential (Δψ) depolarizing agents inhibit maturation
نویسندگان
چکیده
منابع مشابه
Pharmacodynamics of non-depolarizing neuromuscular blocking agents.
When a clinical dose of a competitive neuromuscular blocking drug is given I.V. to a patient, a period of latency is followed by a progressive onset of blockade until a maximum is reached after several minutes. Thereafter, the intensity of block declines gradually. The precise relationship between the dose of drug and the time-course of the effect is complex, being dependent upon both pharmacok...
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20 In immature neurons activation of ionotropic GABA receptors induces depolarizing 21 membrane responses due to a high intracellular Cl-concentration ([Cl-] i). However, it 22 is difficult to draw conclusions about the functional consequences of subthreshold 23 GABAergic depolarizations, since GABAergic membrane shunting and additional 24 effects on voltage-dependent ion channels or action pot...
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Electrical stimulation of parasympathetic nerve (PSN) efferent fibers in the glossopharyngeal nerve induced a slow depolarizing synaptic potential (DSP) in frog taste cells under hypoxia. The objective of this study is to examine the interaction between a gustatory depolarizing receptor potential (GDRP) and a slow DSP. The amplitude of slow DSP added to a tastant-induced GDRP of 10 mV was suppr...
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Previous experiments established that when the unicellular green alga Chlorella NC64A is inoculated with two viruses, usually only one virus replicates in a single cell. That is, the viruses mutually exclude one another. In the current study, we explore the possibility that virus-induced host membrane depolarization, at least partially caused by a virus-encoded K(+) channel (Kcv), is involved i...
متن کاملThe Ionic Basis of the Depolarizing Mechanoreceptor Potential of Paramecium
A depolarizing receptor potential produced by mechanical stimulation was studied in pawn mutants of Paramecium tetraurelia bathed in TEA solution. The potential was dependent upon the strength of the mechanical stimulation until a maximum response was reached. The maximum value was dependent on the concentration of external Ca. Discounting the change in resting potential (attributable to change...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1982
ISSN: 0014-5793
DOI: 10.1016/0014-5793(82)81069-7